Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis

Necroptosis is a programmed cell death pathway triggered by activation of receptor interacting protein kinase 3 (RIPK3), which phosphorylates and activates the mixed lineage kinase-like domain pseudokinase, MLKL, to rupture or permeabilize the plasma membrane. Necroptosis is an inflammatory pathway...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Vis Exp
Main Authors: McNamara, Dan E., Quarato, Giovanni, Guy, Cliff S., Green, Douglas R., Moldoveanu, Tudor
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2018
Teme:
Retraction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126679/
https://ncbi.nlm.nih.gov/pubmed/30148498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58088
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