MLKL requires the inositol phosphate code to execute necroptosis

Necroptosis is an important form of lytic cell death triggered by injury and infection, yet whether mixed lineage kinase domain-like (MLKL) is sufficient to execute this pathway is unknown. In a genetic selection for human cell mutants defective for MLKL-dependent necroptosis, we identified mutation...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Cell
मुख्य लेखकों: Dovey, Cole M., Diep, Jonathan, Clarke, Bradley P., Hale, Andrew T., McNamara, Dan E., Guo, Hongyan, Brown, Nathaniel W., Cao, Jennifer Yinuo, Grace, Christy R., Gough, Peter J., Bertin, John, Dixon, Scott J., Fiedler, Dorothea, Mocarski, Edward S., Kaiser, William J., Moldoveanu, Tudor, York, John D., Carette, Jan E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994928/
https://ncbi.nlm.nih.gov/pubmed/29883610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.05.010
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