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Early and Selective Activation and Subsequent Alterations to the Unfolded Protein Response in Down Syndrome Mouse Models

Down syndrome (DS) is the most common chromosomal disorder and the leading genetic cause of intellectual disability in humans, which results from the triplication of chromosome 21. DS individuals have an increased risk of developing Alzheimer’s disease (AD)-like pathology and dementia by the age of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Alzheimers Dis
Egile Nagusiak: Lanzillotta, Chiara, Tramutola, Antonella, Meier, Shelby, Schmitt, Frederick, Barone, Eugenio, Perluigi, Marzia, Di Domenico, Fabio, Abisambra, Jose F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988365/
https://ncbi.nlm.nih.gov/pubmed/29439332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170617
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