Llwytho...

Early and Selective Activation and Subsequent Alterations to the Unfolded Protein Response in Down Syndrome Mouse Models

Down syndrome (DS) is the most common chromosomal disorder and the leading genetic cause of intellectual disability in humans, which results from the triplication of chromosome 21. DS individuals have an increased risk of developing Alzheimer’s disease (AD)-like pathology and dementia by the age of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Alzheimers Dis
Prif Awduron: Lanzillotta, Chiara, Tramutola, Antonella, Meier, Shelby, Schmitt, Frederick, Barone, Eugenio, Perluigi, Marzia, Di Domenico, Fabio, Abisambra, Jose F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988365/
https://ncbi.nlm.nih.gov/pubmed/29439332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170617
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