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Early and Selective Activation and Subsequent Alterations to the Unfolded Protein Response in Down Syndrome Mouse Models

Down syndrome (DS) is the most common chromosomal disorder and the leading genetic cause of intellectual disability in humans, which results from the triplication of chromosome 21. DS individuals have an increased risk of developing Alzheimer’s disease (AD)-like pathology and dementia by the age of...

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Bibliografski detalji
Izdano u:J Alzheimers Dis
Glavni autori: Lanzillotta, Chiara, Tramutola, Antonella, Meier, Shelby, Schmitt, Frederick, Barone, Eugenio, Perluigi, Marzia, Di Domenico, Fabio, Abisambra, Jose F.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988365/
https://ncbi.nlm.nih.gov/pubmed/29439332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170617
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