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It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease

Free radical-mediated damage to macromolecules and the resulting oxidative modification of different cellular components are a common feature of aging, and this process becomes much more pronounced in age-associated pathologies, including Alzheimer disease (AD). In particular, proteins are particula...

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Bibliografiske detaljer
Udgivet i:Oxid Med Cell Longev
Main Authors: Tramutola, Antonella, Di Domenico, Fabio, Barone, Eugenio, Perluigi, Marzia, Butterfield, D. Allan
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736377/
https://ncbi.nlm.nih.gov/pubmed/26881020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2756068
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