Megakaryocyte and Osteoblast Interactions Modulate Bone Mass and Hematopoiesis

Emerging evidence demonstrates that megakaryocytes (MK) play key roles in regulating skeletal homeostasis and hematopoiesis. To test if the loss of MK negatively impacts osteoblastogenesis and hematopoiesis, we generated conditional knockout mice where Mpl, the receptor for the main MK growth factor...

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Detalles Bibliográficos
Publicado en:Stem Cells Dev
Main Authors: Alvarez, Marta B., Xu, LinLin, Childress, Paul J., Maupin, Kevin A., Mohamad, Safa F., Chitteti, Brahmananda R., Himes, Evan, Olivos, David J., Cheng, Ying-Hua, Conway, Simon J., Srour, Edward F., Kacena, Melissa A.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2018
Assuntos:
Original Research Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962330/
https://ncbi.nlm.nih.gov/pubmed/29631496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2017.0178
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