Megakaryocyte and Osteoblast Interactions Modulate Bone Mass and Hematopoiesis

Emerging evidence demonstrates that megakaryocytes (MK) play key roles in regulating skeletal homeostasis and hematopoiesis. To test if the loss of MK negatively impacts osteoblastogenesis and hematopoiesis, we generated conditional knockout mice where Mpl, the receptor for the main MK growth factor...

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Bibliografiske detaljer
Udgivet i:Stem Cells Dev
Main Authors: Alvarez, Marta B., Xu, LinLin, Childress, Paul J., Maupin, Kevin A., Mohamad, Safa F., Chitteti, Brahmananda R., Himes, Evan, Olivos, David J., Cheng, Ying-Hua, Conway, Simon J., Srour, Edward F., Kacena, Melissa A.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2018
Fag:
Original Research Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962330/
https://ncbi.nlm.nih.gov/pubmed/29631496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2017.0178
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