Megakaryocyte and Osteoblast Interactions Modulate Bone Mass and Hematopoiesis

Emerging evidence demonstrates that megakaryocytes (MK) play key roles in regulating skeletal homeostasis and hematopoiesis. To test if the loss of MK negatively impacts osteoblastogenesis and hematopoiesis, we generated conditional knockout mice where Mpl, the receptor for the main MK growth factor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stem Cells Dev
Prif Awduron: Alvarez, Marta B., Xu, LinLin, Childress, Paul J., Maupin, Kevin A., Mohamad, Safa F., Chitteti, Brahmananda R., Himes, Evan, Olivos, David J., Cheng, Ying-Hua, Conway, Simon J., Srour, Edward F., Kacena, Melissa A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2018
Pynciau:
Original Research Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962330/
https://ncbi.nlm.nih.gov/pubmed/29631496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2017.0178
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