Megakaryocytes promote osteoclastogenesis in aging

Megakaryocytes (MKs) support bone formation by stimulating osteoblasts (OBs) and inhibiting osteoclasts (OCs). Aging results in higher bone resorption, leading to bone loss. Whereas previous studies showed the effects of aging on MK-mediated bone formation, the effects of aging on MK-mediated OC for...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Kanagasabapathy, Deepa, Blosser, Rachel J., Maupin, Kevin A., Hong, Jung Min, Alvarez, Marta, Ghosh, Joydeep, Mohamad, Safa F., Aguilar-Perez, Alexandra, Srour, Edward F., Kacena, Melissa A., Bruzzaniti, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425434/
https://ncbi.nlm.nih.gov/pubmed/32634116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103595
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