Osteomacs interact with megakaryocytes and osteoblasts to regulate murine hematopoietic stem cell function

Networking between hematopoietic stem cells (HSCs) and cells of the hematopoietic niche is critical for stem cell function and maintenance of the stem cell pool. We characterized calvariae-resident osteomacs (OMs) and their interaction with megakaryocytes to sustain HSC function and identified disti...

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Pubblicato in:Blood Adv
Autori principali: Mohamad, Safa F., Xu, Linlin, Ghosh, Joydeep, Childress, Paul J., Abeysekera, Irushi, Himes, Evan R., Wu, Hao, Alvarez, Marta B., Davis, Korbin M., Aguilar-Perez, Alexandra, Hong, Jung Min, Bruzzaniti, Angela, Kacena, Melissa A., Srour, Edward F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2017
Soggetti:
Hematopoiesis and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728639/
https://ncbi.nlm.nih.gov/pubmed/29296903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017011304
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