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The Changing Balance Between Osteoblastogenesis and Adipogenesis in Aging and its Impact on Hematopoiesis

Osteoblasts (OBs) and adipocytes (APs) share a common mesenchymal ancestor. It is now clear that mesenchymal stem cell (MSC) maturation along the OB lineage comes at the expense of adipogenesis and vice versa. During aging, this balance increasingly favors the formation of APs. Hematopoiesis also sl...

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Bibliographic Details
Main Authors: Bethel, Monique, Chitteti, Brahmananda R., Srour, Edward F., Kacena, Melissa A.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643998/
https://ncbi.nlm.nih.gov/pubmed/23423562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11914-013-0135-6
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