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Genomic and Proteomic Analysis of the Impact of Mitotic Quiescence on the Engraftment of Human CD34(+) Cells

It is well established that in adults, long-term repopulating hematopoietic stem cells (HSC) are mitotically quiescent cells that reside in specialized bone marrow (BM) niches that maintain the dormancy of HSC. Our laboratory demonstrated that the engraftment potential of human HSC (CD34(+) cells) f...

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Detalhes bibliográficos
Main Authors: Chitteti, Brahmananda Reddy, Liu, Yunlong, Srour, Edward F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049784/
https://ncbi.nlm.nih.gov/pubmed/21408179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017498
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