Llwytho...

Transient and Local Expression of Chemokine and Immune Checkpoint Traps To Treat Pancreatic Cancer

Pancreatic tumors are known to be resistant to immunotherapy due to the extensive immune suppressive tumor microenvironment (TME). We hypothesized that CXCL12 and PD-L1 are two key molecules controlling the immunosuppressive TME. Fusion proteins, called traps, designed to bind with these two molecul...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Nano
Prif Awduron: Miao, Lei, Li, Jingjing, Liu, Qi, Feng, Richard, Das, Manisit, Lin, C. Michael, Goodwin, Tyler J., Dorosheva, Oleksandra, Liu, Rihe, Huang, Leaf
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961942/
https://ncbi.nlm.nih.gov/pubmed/28809532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.7b01786
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!