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Nanoparticle Delivery of RIG-I Agonist Enables Effective and Safe Adjuvant Therapy in Pancreatic Cancer

Local immunomodulation can be a promising strategy to augment the efficacy and decrease off-target toxicities associated with cancer treatment. Pancreatic cancer is resistant to immunotherapies due to the immunosuppressive tumor microenvironment. Herein, we investigated a therapeutic approach involv...

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Détails bibliographiques
Publié dans:Mol Ther
Auteurs principaux: Das, Manisit, Shen, Limei, Liu, Qi, Goodwin, Tyler J., Huang, Leaf
Format: Artigo
Langue:Inglês
Publié: American Society of Gene & Cell Therapy 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401191/
https://ncbi.nlm.nih.gov/pubmed/30545600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.11.012
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