Učitavanje...
Tumor neoantigen heterogeneity impacts bystander immune inhibition of pancreatic cancer growth
The immunogenic clonal-fraction threshold in heterogeneous solid-tumor required to induce effective bystander-killing of non-immunogenic subclones is unknown. Pancreatic cancer poses crucial challenges for immune therapeutic interventions due to low mutational-burden and consequent lack of neoantige...
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| Izdano u: | Transl Oncol |
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| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Neoplasia Press
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7475277/ https://ncbi.nlm.nih.gov/pubmed/32862105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100856 |
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