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Liver Specific Gene Immunotherapies Resolve Immune Suppressive Ectopic Lymphoid Structures of Liver Metastases and Prolong Survival

The ability to generate potent immunotherapies locally and transiently for the treatment of cancers is a promising strategy to improve efficacy and decrease off-target toxicities. Here, we explored an alternative approach for the delivery of immunotherapeutic agents, in which we deliver the pDNA of...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Goodwin, Tyler J., Shen, Limei, Hu, Mengying, Li, Jingjing, Feng, Richard, Dorosheva, Oleksandra, Liu, Rihe, Huang, Leaf
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557391/
https://ncbi.nlm.nih.gov/pubmed/28700955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.07.007
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