Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap

Although great success has been obtained in the clinic, the current immune checkpoint inhibitors still face two challenging problems: low response rate and immune-related adverse effects (irAEs). Here we report the combination of immunogenic chemotherapy and locally expressed PD-L1 trap fusion prote...

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Publicado en:Nat Commun
Main Authors: Song, Wantong, Shen, Limei, Wang, Ying, Liu, Qi, Goodwin, Tyler J., Li, Jingjing, Dorosheva, Olekasandra, Liu, Tianzhou, Liu, Rihe, Huang, Leaf
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993831/
https://ncbi.nlm.nih.gov/pubmed/29884866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04605-x
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