Liver Specific Gene Immunotherapies Resolve Immune Suppressive Ectopic Lymphoid Structures of Liver Metastases and Prolong Survival

The ability to generate potent immunotherapies locally and transiently for the treatment of cancers is a promising strategy to improve efficacy and decrease off-target toxicities. Here, we explored an alternative approach for the delivery of immunotherapeutic agents, in which we deliver the pDNA of...

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Vydáno v:Biomaterials
Hlavní autoři: Goodwin, Tyler J., Shen, Limei, Hu, Mengying, Li, Jingjing, Feng, Richard, Dorosheva, Oleksandra, Liu, Rihe, Huang, Leaf
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557391/
https://ncbi.nlm.nih.gov/pubmed/28700955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.07.007
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