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Efficacies of Cabotegravir and Bictegravir against drug-resistant HIV-1 integrase mutants
BACKGROUND: Integrase strand transfer inhibitors (INSTIs) are the class of antiretroviral (ARV) drugs most recently approved by the FDA for the treatment of HIV-1 infections. INSTIs block the strand transfer reaction catalyzed by HIV-1 integrase (IN) and have been shown to potently inhibit infection...
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| Veröffentlicht in: | Retrovirology |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5956922/ https://ncbi.nlm.nih.gov/pubmed/29769116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-018-0420-7 |
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