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HIV-1 Integrase Inhibitors That Are Active against Drug-Resistant Integrase Mutants
The currently recommended first-line therapy for HIV-1-infected patients is an integrase (IN) strand transfer inhibitor (INSTI), either dolutegravir (DTG) or bictegravir (BIC), in combination with two nucleoside reverse transcriptase inhibitors (NRTIs). Both DTG and BIC potently inhibit most INSTI-r...
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| Publicado no: | Antimicrob Agents Chemother |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7449158/ https://ncbi.nlm.nih.gov/pubmed/32601157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00611-20 |
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