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HIV-1 Integrase Inhibitors That Are Active against Drug-Resistant Integrase Mutants
The currently recommended first-line therapy for HIV-1-infected patients is an integrase (IN) strand transfer inhibitor (INSTI), either dolutegravir (DTG) or bictegravir (BIC), in combination with two nucleoside reverse transcriptase inhibitors (NRTIs). Both DTG and BIC potently inhibit most INSTI-r...
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| Izdano u: | Antimicrob Agents Chemother |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7449158/ https://ncbi.nlm.nih.gov/pubmed/32601157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00611-20 |
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