HIV-1 Integrase Inhibitors That Are Active against Drug-Resistant Integrase Mutants

The currently recommended first-line therapy for HIV-1-infected patients is an integrase (IN) strand transfer inhibitor (INSTI), either dolutegravir (DTG) or bictegravir (BIC), in combination with two nucleoside reverse transcriptase inhibitors (NRTIs). Both DTG and BIC potently inhibit most INSTI-r...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Smith, Steven J., Zhao, Xue Zhi, Passos, Dario Oliveira, Lyumkis, Dmitry, Burke, Terrence R., Hughes, Stephen H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2020
Konular:
Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449158/
https://ncbi.nlm.nih.gov/pubmed/32601157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00611-20
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