Antiviral Activity of Bictegravir and Cabotegravir against Integrase Inhibitor-Resistant SIVmac239 and HIV-1

Animal models are essential to study novel antiretroviral drugs, resistance-associated mutations (RAMs), and treatment strategies. Bictegravir (BIC) is a novel potent integrase strand transfer inhibitor (INSTI) that has shown promising results against HIV-1 infection in vitro and in vivo and against...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Hassounah, Said A., Alikhani, Ahmad, Oliveira, Maureen, Bharaj, Simrat, Ibanescu, Ruxandra-Ilinca, Osman, Nathan, Xu, Hong-Tao, Brenner, Bluma G., Mesplède, Thibault, Wainberg, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700299/
https://ncbi.nlm.nih.gov/pubmed/28923862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01695-17
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