Antiviral Activity of Bictegravir and Cabotegravir against Integrase Inhibitor-Resistant SIVmac239 and HIV-1

Animal models are essential to study novel antiretroviral drugs, resistance-associated mutations (RAMs), and treatment strategies. Bictegravir (BIC) is a novel potent integrase strand transfer inhibitor (INSTI) that has shown promising results against HIV-1 infection in vitro and in vivo and against...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Hassounah, Said A., Alikhani, Ahmad, Oliveira, Maureen, Bharaj, Simrat, Ibanescu, Ruxandra-Ilinca, Osman, Nathan, Xu, Hong-Tao, Brenner, Bluma G., Mesplède, Thibault, Wainberg, Mark A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700299/
https://ncbi.nlm.nih.gov/pubmed/28923862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01695-17
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