Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle–regulated exocytosis in mast cells

Mast cells (MCs) play pivotal roles in many inflammatory conditions including infections, anaphylaxis, and asthma. MCs store immunoregulatory compounds in their large cytoplasmic granules and, upon stimulation, secrete them via regulated exocytosis. Exocytosis in many cells requires the participatio...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Gutierrez, Berenice A., Chavez, Miguel A., Rodarte, Alejandro I., Ramos, Marco A., Dominguez, Andrea, Petrova, Youlia, Davalos, Alfredo J., Costa, Renan M., Elizondo, Ramon, Tuvim, Michael J., Dickey, Burton F., Burns, Alan R., Heidelberger, Ruth, Adachi, Roberto
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2018
Предметы:
Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950006/
https://ncbi.nlm.nih.gov/pubmed/29599294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002455
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