Syntaxin 3, but not syntaxin 4, is required for mast cell–regulated exocytosis, where it plays a primary role mediating compound exocytosis

Mast cells (MCs) participate in allergy, inflammation, and defense against pathogens. They release multiple immune mediators via exocytosis, a process that requires SNARE proteins, including syntaxins (Stxs). The identity of the Stxs involved in MC exocytosis remains controversial. Here, we studied...

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Publicado en:J Biol Chem
Autores principales: Sanchez, Elizabeth, Gonzalez, Erika A., Moreno, David S., Cardenas, Rodolfo A., Ramos, Marco A., Davalos, Alfredo J., Manllo, John, Rodarte, Alejandro I., Petrova, Youlia, Moreira, Daniel C., Chavez, Miguel A., Tortoriello, Alejandro, Lara, Adolfo, Gutierrez, Berenice A., Burns, Alan R., Heidelberger, Ruth, Adachi, Roberto
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Membrane Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398129/
https://ncbi.nlm.nih.gov/pubmed/30563839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005532
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