Syntaxin 3, but not syntaxin 4, is required for mast cell–regulated exocytosis, where it plays a primary role mediating compound exocytosis

Mast cells (MCs) participate in allergy, inflammation, and defense against pathogens. They release multiple immune mediators via exocytosis, a process that requires SNARE proteins, including syntaxins (Stxs). The identity of the Stxs involved in MC exocytosis remains controversial. Here, we studied...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sanchez, Elizabeth, Gonzalez, Erika A., Moreno, David S., Cardenas, Rodolfo A., Ramos, Marco A., Davalos, Alfredo J., Manllo, John, Rodarte, Alejandro I., Petrova, Youlia, Moreira, Daniel C., Chavez, Miguel A., Tortoriello, Alejandro, Lara, Adolfo, Gutierrez, Berenice A., Burns, Alan R., Heidelberger, Ruth, Adachi, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398129/
https://ncbi.nlm.nih.gov/pubmed/30563839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005532
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