Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle–regulated exocytosis in mast cells

Mast cells (MCs) play pivotal roles in many inflammatory conditions including infections, anaphylaxis, and asthma. MCs store immunoregulatory compounds in their large cytoplasmic granules and, upon stimulation, secrete them via regulated exocytosis. Exocytosis in many cells requires the participatio...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gutierrez, Berenice A., Chavez, Miguel A., Rodarte, Alejandro I., Ramos, Marco A., Dominguez, Andrea, Petrova, Youlia, Davalos, Alfredo J., Costa, Renan M., Elizondo, Ramon, Tuvim, Michael J., Dickey, Burton F., Burns, Alan R., Heidelberger, Ruth, Adachi, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950006/
https://ncbi.nlm.nih.gov/pubmed/29599294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002455
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