Munc18-2, but not Munc18-1 or Munc18-3, regulates platelet exocytosis, hemostasis, and thrombosis

Platelet degranulation, a form of regulated exocytosis, is crucial for hemostasis and thrombosis. Exocytosis in platelets is mediated by SNARE proteins, and in most mammalian cells this process is controlled by Munc18 (mammalian homolog of Caenorhabditis elegans uncoordinated gene 18) proteins. Plat...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Cardenas, Eduardo I., Gonzalez, Ricardo, Breaux, Keegan, Da, Qi, Gutierrez, Berenice A., Ramos, Marco A., Cardenas, Rodolfo A., Burns, Alan R., Rumbaut, Rolando E., Adachi, Roberto
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442067/
https://ncbi.nlm.nih.gov/pubmed/30696774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006922
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires