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Munc18-2, but not Munc18-1 or Munc18-3, regulates platelet exocytosis, hemostasis, and thrombosis

Platelet degranulation, a form of regulated exocytosis, is crucial for hemostasis and thrombosis. Exocytosis in platelets is mediated by SNARE proteins, and in most mammalian cells this process is controlled by Munc18 (mammalian homolog of Caenorhabditis elegans uncoordinated gene 18) proteins. Plat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Cardenas, Eduardo I., Gonzalez, Ricardo, Breaux, Keegan, Da, Qi, Gutierrez, Berenice A., Ramos, Marco A., Cardenas, Rodolfo A., Burns, Alan R., Rumbaut, Rolando E., Adachi, Roberto
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442067/
https://ncbi.nlm.nih.gov/pubmed/30696774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006922
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