Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells

Airway mucin secretion and MC (mast cell) degranulation must be tightly controlled for homoeostasis of the lungs and immune system respectively. We found the exocytic protein Munc18b to be highly expressed in mouse airway epithelial cells and MCs, and localized to the apical pole of airway secretory...

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Autores principales: Kim, Kyubo, Petrova, Youlia M., Scott, Brenton L., Nigam, Rupesh, Agrawal, Anurag, Evans, Christopher M., Azzegagh, Zoulikha, Gomez, Alejandra, Rodarte, Elsa M., Olkkonen, Vesa M., Bagirzadeh, Rustam, Piccotti, Lucia, Ren, Binhui, Yoon, Joo-Heon, McNew, James A., Adachi, Roberto, Tuvim, Michael J., Dickey, Burton F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430001/
https://ncbi.nlm.nih.gov/pubmed/22694344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120057
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