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HDAC-mediated deacetylation of KLF5 associates with its proteasomal degradation
Krüppel-like factor 5 (KLF5) is a basic transcription factor that regulates diverse cellular processes during tumor development. Acetylation of KLF5 at lysine 369 (K369) reverses its function from promoting to suppressing cell proliferation and tumor growth. In this study, we examined the regulation...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940529/ https://ncbi.nlm.nih.gov/pubmed/29679567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.04.153 |
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