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Klf5 acetylation regulates luminal differentiation of basal progenitors in prostate development and regeneration

Prostate development depends on balanced cell proliferation and differentiation, and acetylated KLF5 is known to alter epithelial proliferation. It remains elusive whether post-translational modifications of transcription factors can differentially determine adult stem/progenitor cell fate. Here we...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhang, Baotong, Ci, Xinpei, Tao, Ran, Ni, Jianping Jenny, Xuan, Xiaoyan, King, Jamie L., Xia, Siyuan, Li, Yixiang, Frierson, Henry F., Lee, Dong-Kee, Xu, Jianming, Osunkoya, Adeboye O., Dong, Jin-Tang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035357/
https://ncbi.nlm.nih.gov/pubmed/32081850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14737-8
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