TGF-β causes Docetaxel resistance in Prostate Cancer via the induction of Bcl-2 by acetylated KLF5 and Protein Stabilization

Prostate cancer is the second leading cause of cancer-related death in the United States. As a first line treatment for hormone-refractory prostate cancer, docetaxel (DTX) treatment leads to suboptimal effect since almost all patients eventually develop DTX resistance. In this study, we investigated...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Li, Yixiang, Zhang, Baotong, Xiang, Lingwei, Xia, Siyuan, Kucuk, Omer, Deng, Xingming, Boise, Lawrence H., Dong, Jin-Tang
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359077/
https://ncbi.nlm.nih.gov/pubmed/32685011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.44567
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