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HDAC-mediated deacetylation of KLF5 associates with its proteasomal degradation
Krüppel-like factor 5 (KLF5) is a basic transcription factor that regulates diverse cellular processes during tumor development. Acetylation of KLF5 at lysine 369 (K369) reverses its function from promoting to suppressing cell proliferation and tumor growth. In this study, we examined the regulation...
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| Pubblicato in: | Biochem Biophys Res Commun |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940529/ https://ncbi.nlm.nih.gov/pubmed/29679567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.04.153 |
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