HDAC-mediated deacetylation of KLF5 associates with its proteasomal degradation

Krüppel-like factor 5 (KLF5) is a basic transcription factor that regulates diverse cellular processes during tumor development. Acetylation of KLF5 at lysine 369 (K369) reverses its function from promoting to suppressing cell proliferation and tumor growth. In this study, we examined the regulation...

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I publikationen:Biochem Biophys Res Commun
Huvudupphovsmän: Tao, Ran, Zhang, Baotong, Li, Yixiang, King, Jamie L., Tian, Ruoyu, Xia, Siyuan, Schiavon, Cara Rae, Dong, Jin-Tang
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940529/
https://ncbi.nlm.nih.gov/pubmed/29679567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.04.153
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