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HDAC4 induces the development of asthma by increasing Slug-upregulated CXCL12 expression through KLF5 deacetylation

BACKGROUND: Asthma is a frequently occurring respiratory disease with an increasing incidence around the world. Airway inflammation and remodeling are important contributors to the occurrence of asthma. We conducted this study aiming at exploring the effect of Histone deacetylase 4 (HDAC4)-mediated...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Wei, Wendi, Chen, Weida, He, Naifeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199843/
https://ncbi.nlm.nih.gov/pubmed/34118928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02812-7
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