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Defects in Actin Dynamics Lead to an Autoinflammatory Condition through the Upregulation of CXCL5

BACKGROUND: Destrin (DSTN) is a member of the ADF/cofilin family of proteins and is an important regulator of actin dynamics. The primary function of destrin is to depolymerize filamentous actin into its monomeric form and promote filament severing. While progress has been made in understanding the...

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Autori principali: Verdoni, Angela M., Smith, Richard S., Ikeda, Akihiro, Ikeda, Sakae
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442876/
https://ncbi.nlm.nih.gov/pubmed/18628996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002701
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