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Defects in Actin Dynamics Lead to an Autoinflammatory Condition through the Upregulation of CXCL5

BACKGROUND: Destrin (DSTN) is a member of the ADF/cofilin family of proteins and is an important regulator of actin dynamics. The primary function of destrin is to depolymerize filamentous actin into its monomeric form and promote filament severing. While progress has been made in understanding the...

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Detalhes bibliográficos
Main Authors: Verdoni, Angela M., Smith, Richard S., Ikeda, Akihiro, Ikeda, Sakae
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442876/
https://ncbi.nlm.nih.gov/pubmed/18628996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002701
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