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Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament severing proteins

Auditory sensory hair cells depend on stereocilia with precisely regulated lengths to detect sound. Since stereocilia are primarily composed of cross-linked, parallel actin filaments, regulated actin dynamics are essential for controlling stereocilia length. Here, we assessed stereocilia actin turno...

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Pubblicato in:Nat Commun
Autori principali: Narayanan, Praveena, Chatterton, Paul, Ikeda, Akihiro, Ikeda, Sakae, Corey, David P., Ervasti, James M., Perrin, Benjamin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523390/
https://ncbi.nlm.nih.gov/pubmed/25897778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7855
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