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HDAC4 induces the development of asthma by increasing Slug-upregulated CXCL12 expression through KLF5 deacetylation

BACKGROUND: Asthma is a frequently occurring respiratory disease with an increasing incidence around the world. Airway inflammation and remodeling are important contributors to the occurrence of asthma. We conducted this study aiming at exploring the effect of Histone deacetylase 4 (HDAC4)-mediated...

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Vydáno v:J Transl Med
Hlavní autoři: Wei, Wendi, Chen, Weida, He, Naifeng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199843/
https://ncbi.nlm.nih.gov/pubmed/34118928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02812-7
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