The impact of whole human blood on the kinetic inertness of platinum(iv) prodrugs – an HPLC-ICP-MS study

The potential advantage of platinum(iv) complexes as alternatives to classical platinum(ii)-based drugs relies on their kinetic stability in the body before reaching the tumor site and on their activation by reduction inside cancer cells. In this study, an analytical workflow has been developed to i...

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Publicat a:Dalton Trans
Autors principals: Theiner, Sarah, Grabarics, Márkó, Galvez, Luis, Varbanov, Hristo P., Sommerfeld, Nadine S., Galanski, Mathea S., Keppler, Bernhard K., Koellensperger, Gunda
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society of Chemistry 2018
Matèries:
Chemistry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933005/
https://ncbi.nlm.nih.gov/pubmed/29560976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7dt04537a
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