The impact of whole human blood on the kinetic inertness of platinum(iv) prodrugs – an HPLC-ICP-MS study

The potential advantage of platinum(iv) complexes as alternatives to classical platinum(ii)-based drugs relies on their kinetic stability in the body before reaching the tumor site and on their activation by reduction inside cancer cells. In this study, an analytical workflow has been developed to i...

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Veröffentlicht in:Dalton Trans
Hauptverfasser: Theiner, Sarah, Grabarics, Márkó, Galvez, Luis, Varbanov, Hristo P., Sommerfeld, Nadine S., Galanski, Mathea S., Keppler, Bernhard K., Koellensperger, Gunda
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society of Chemistry 2018
Schlagworte:
Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933005/
https://ncbi.nlm.nih.gov/pubmed/29560976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7dt04537a
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