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The impact of whole human blood on the kinetic inertness of platinum(iv) prodrugs – an HPLC-ICP-MS study

The potential advantage of platinum(iv) complexes as alternatives to classical platinum(ii)-based drugs relies on their kinetic stability in the body before reaching the tumor site and on their activation by reduction inside cancer cells. In this study, an analytical workflow has been developed to i...

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Bibliografiske detaljer
Udgivet i:Dalton Trans
Main Authors: Theiner, Sarah, Grabarics, Márkó, Galvez, Luis, Varbanov, Hristo P., Sommerfeld, Nadine S., Galanski, Mathea S., Keppler, Bernhard K., Koellensperger, Gunda
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society of Chemistry 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933005/
https://ncbi.nlm.nih.gov/pubmed/29560976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7dt04537a
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