The impact of whole human blood on the kinetic inertness of platinum(iv) prodrugs – an HPLC-ICP-MS study

The potential advantage of platinum(iv) complexes as alternatives to classical platinum(ii)-based drugs relies on their kinetic stability in the body before reaching the tumor site and on their activation by reduction inside cancer cells. In this study, an analytical workflow has been developed to i...

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Dettagli Bibliografici
Pubblicato in:Dalton Trans
Autori principali: Theiner, Sarah, Grabarics, Márkó, Galvez, Luis, Varbanov, Hristo P., Sommerfeld, Nadine S., Galanski, Mathea S., Keppler, Bernhard K., Koellensperger, Gunda
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society of Chemistry 2018
Soggetti:
Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933005/
https://ncbi.nlm.nih.gov/pubmed/29560976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7dt04537a
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