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The impact of whole human blood on the kinetic inertness of platinum(iv) prodrugs – an HPLC-ICP-MS study

The potential advantage of platinum(iv) complexes as alternatives to classical platinum(ii)-based drugs relies on their kinetic stability in the body before reaching the tumor site and on their activation by reduction inside cancer cells. In this study, an analytical workflow has been developed to i...

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Detalhes bibliográficos
Publicado no:Dalton Trans
Main Authors: Theiner, Sarah, Grabarics, Márkó, Galvez, Luis, Varbanov, Hristo P., Sommerfeld, Nadine S., Galanski, Mathea S., Keppler, Bernhard K., Koellensperger, Gunda
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933005/
https://ncbi.nlm.nih.gov/pubmed/29560976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7dt04537a
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