Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1

Telomeric repeat binding factor 1 (TRF1) is essential to the maintenance of telomere chromatin structure and integrity. However, how telomere integrity is maintained, especially in response to damage, remains poorly understood. Here, we identify Nek7, a member of the Never in Mitosis Gene A (NIMA) k...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Tan, Rong, Nakajima, Satoshi, Wang, Qun, Sun, Hongxiang, Xue, Jing, Wu, Jian, Hellwig, Sabine, Zeng, Xuemei, Yates, Nathan A., Smithgall, Thomas E., Lei, Ming, Jiang, Yu, Levine, Arthur S., Su, Bing, Lan, Li
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924698/
https://ncbi.nlm.nih.gov/pubmed/28216227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.01.015
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker