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Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2
The ends of linear chromosomes are capped by protein–DNA complexes termed telomeres. Telomere repeat binding factors 1 and 2 (TRF1 and TRF2) bind specifically to duplex telomeric DNA and are critical components of functional telomeres. Consequences of telomere dysfunction include genomic instability...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549571/ https://ncbi.nlm.nih.gov/pubmed/15731343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki273 |
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