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The impact of oxidative DNA damage and stress on telomere homeostasis
Telomeres are dynamic nucleoprotein-DNA structures that cap and protect linear chromosome ends. Because telomeres shorten progressively with each replication, they impose a functional limit on the number of times a cell can divide. Critically short telomeres trigger cellular senescence in normal cel...
Gardado en:
| Publicado en: | Mech Ageing Dev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6162185/ https://ncbi.nlm.nih.gov/pubmed/29604323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2018.03.013 |
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