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Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts
Ultraviolet light induces cyclobutane pyrimidine dimers (CPD) and pyrimidine(6–4)pyrimidone photoproducts, which interfere with DNA replication and transcription. Nucleotide excision repair (NER) removes these photoproducts, but whether NER functions at telomeres is unresolved. Here we use immunospo...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4566151/ https://ncbi.nlm.nih.gov/pubmed/26351258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9214 |
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