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Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts
Ultraviolet light induces cyclobutane pyrimidine dimers (CPD) and pyrimidine(6–4)pyrimidone photoproducts, which interfere with DNA replication and transcription. Nucleotide excision repair (NER) removes these photoproducts, but whether NER functions at telomeres is unresolved. Here we use immunospo...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Pub. Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4566151/ https://ncbi.nlm.nih.gov/pubmed/26351258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9214 |
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