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Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts

Ultraviolet light induces cyclobutane pyrimidine dimers (CPD) and pyrimidine(6–4)pyrimidone photoproducts, which interfere with DNA replication and transcription. Nucleotide excision repair (NER) removes these photoproducts, but whether NER functions at telomeres is unresolved. Here we use immunospo...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Parikh, Dhvani, Fouquerel, Elise, Murphy, Connor T., Wang, Hong, Opresko, Patricia L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Pub. Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566151/
https://ncbi.nlm.nih.gov/pubmed/26351258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9214
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