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A role for WRN in telomere-based DNA damage responses

Telomeres cap the ends of eukaryotic chromosomes and prevent them from being recognized as DNA breaks. We have shown that certain DNA damage responses induced during senescence and, at times of telomere uncapping, also can be induced by treatment of cells with small DNA oligonucleotides homologous t...

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Detalhes bibliográficos
Main Authors: Eller, Mark S., Liao, Xiaodong, Liu, SuiYang, Hanna, Kendra, Bäckvall, Helena, Opresko, Patricia L., Bohr, Vilhelm A., Gilchrest, Barbara A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1586178/
https://ncbi.nlm.nih.gov/pubmed/17015833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607332103
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