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A role for WRN in telomere-based DNA damage responses
Telomeres cap the ends of eukaryotic chromosomes and prevent them from being recognized as DNA breaks. We have shown that certain DNA damage responses induced during senescence and, at times of telomere uncapping, also can be induced by treatment of cells with small DNA oligonucleotides homologous t...
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Auteurs principaux: | , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
National Academy of Sciences
2006
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1586178/ https://ncbi.nlm.nih.gov/pubmed/17015833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607332103 |
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